Preparation of aryllithium compounds by metalation
US4006187A · kind A · utility
11Cited by
4References
11Claims
0Family size
Assignee
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Key dates
| Filing date | Oct 6, 1971 |
| Grant date | Feb 1, 1977 |
| Priority date | — |
| Expiry date | Oct 6, 1991 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F1/02
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Process of metalating benzene containing alkyl, alkoxy or dialkylamino substituents, such as toluene, anisole and N,N-dimethyl-aniline, with an organolithium compound such as sec-butyllithium adducts with styrene, in the presence of a tertiary alkyl amine (containing no methyl groups) such as triethylamine, the ratio of lithium in said organolithium compound to the tertiary alkyl amine being 1 gram atom of the lithium to from about 0.25 to about 4 gram moles of the tertiary alkyl amine.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.