Nicotinamide production
US4008241A · kind A · utility
6Cited by
0References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 2, 1975 |
| Grant date | Feb 15, 1977 |
| Priority date | — |
| Expiry date | Sep 2, 1995 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D213/81
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Nicotinamide is produced by aqueous ammonia hydrolysis of nicotinonitrile wherein the conversion is limited to at least 30% and no greater than 70%, with the nicotinonitrile concentration, expressed as weight product amide per 100 pounds of water, being at least 100 parts and no greater than 300 parts, with the hydrolysis being effected in the presence of ammonium nicotinate in an amount sufficient to essentially eliminate net production thereof. Ammonia and nicotinonitrile are stripped from the hydrolysis effluent, and nicotinamide recovered, by crystallization, from the stripped hydrolysis effluent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.