Substituted ureas and thioureas and pharmaceutical compositions thereof
US4008326A · kind A · utility
4Cited by
0References
15Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jun 25, 1975 |
| Grant date | Feb 15, 1977 |
| Priority date | — |
| Expiry date | Jun 25, 1995 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C405/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A method of improving the endogenous production of prostaglandins by a mammal is disclosed, which comprises administering to the mammal an effective amount of 1-pyridylalkyl-3-naphthyl-2(thio)ureas. Disclosed also are novel substituted 1-pyridylalkyl-3-naphthyl-2(thio)ureas and therapeutic compositions thereof which are useful in carrying out the method of the invention. Disclosed also are methods of treating mammals for clinical conditions responsive to prostaglandins, such as, for example, male infertility, epidermal injuries, atonic uterine bleeding, thromboembolic disease and like clinical conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.