Patent · US Expired

Isoxazole substituted nitroimidazoles

US4010176A · kind A · utility

20Cited by
5References
2Claims
0Family size

Assignee

Inventors

Key dates

Filing dateJul 30, 1975
Grant dateMar 1, 1977
Priority date—
Expiry dateJul 30, 1995

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D233/95
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Novel substituted nitroimidazoles are provided, for example, 2-(4,5-substituted-isoxazol-3-yl)-1-substituted-5-nitroimidazole; 2-(4,5-disubstituted-.DELTA..sup.2 -isoxazolin-3-yl)-1-substituted-5-nitroimidazole; or 2-(4,5-disubstituted-2-loweralkyl-isoxazolidin-3-yl)-1-substituted-5-nitro imidazole. These compounds have antibacterial and antiprotozoal activity, especially against human and animal trypanosomiasis and trichomoniasis.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.