Patent · US Expired

Des-(Ala.sup.1, Gly.sup.2,Lys.sup.4 -Srif, Des-(Ala.sup.1, Gly.sup.2, Lys.sup.4)-D-Trp.sup.8 -Srif and intermediates

US4011207A · kind A · utility

7Cited by
1References
8Claims
0Family size

Assignee

Inventor

Key dates

Filing dateMar 8, 1976
Grant dateMar 8, 1977
Priority date
Expiry dateMar 8, 1996

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S930/16
  • WIPO fieldPharmaceuticals
  • WIPO sectorChemistry

Abstract

The undecapeptide H-Cys-Asn-Phe-Phe-Trp-Lys-Thr-Phe-Thr-Ser-Cys-OH, its D-Trp.sup.8 analogue, their oxidized forms and intermediates obtained in their synthesis are described. These undecapeptides inhibit the secretion of the hormone somatotropin (growth hormone).

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.