Patent · US Expired

Orally active bronchospasmolytic compounds

US4011258A · kind A · utility

17Cited by

1References

3Claims

0Family size

Assignee

DRACO LTD. · SE

Inventors

Kjell I. L. Wetterlin · Södra Sandby, SE
Leif Svensson · Lund, SE

Key dates

Filing date	Jul 7, 1975
Grant date	Mar 8, 1977
Priority date	—
Expiry date	Jul 7, 1995

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07C45/63
WIPO fieldPharmaceuticals
WIPO sectorChemistry

Abstract

Novel compounds are disclosed having useful activity as bronchodilators of improved longevity of action and reduced incidence of side effects. These compounds are described by the formula: ##STR1## wherein R.sub.1 is a member of the class consisting of tertiary butyl and cyclobutyl, and R.sub.2 is a hydrogen or 2 to 5 carbon atom acyl radical, and pharmaceutically acceptable salts thereof. The activity of these compounds is compared to previously known bronchodilators such as 1-(3', 5'-dihydroxyphenyl)-2-(isopropylamino)-ethanol, having the common name orciprenaline, and 1-(3', 4'-dihydroxyphenyl-2-isopropylamino-ethanol, having the common name isoprenaline.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.