Novel methylene steroids

US4012510A · kind A · utility

Assignee

• SCHERING CORPORATION · US

Inventors

• Rudolf Wiechert · Berlin, DE
• Klaus Kieslich · Braunschweig, DE
• Henning Koch

Key dates

• Filing date: Nov 10, 1975
• Grant date: Mar 15, 1977
• Expiry date: Nov 10, 1995

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07J53/008
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Methylene steroids of the formula ##STR1## wherein X is H, F or CH.sub.3 ; Y is hydroxymethylene, alkanoyloxymethylene or carbonyl; R.sub.1 is H, OH or alkanoyloxy; and R.sub.2 is H, OH or esterified OH, possess topical anti-inflammatory activity.