Immobilized enzymes

US4013511A · kind A · utility

Assignee

• YEDA RESEARCH AND DEVELOPMENT CO. LTD. · IL

Inventors

• Leon Goldstein · Chaville, FR
• Ephraim Katzir (Katchalski) · Rehovot, IL
• Yehuda Levin · Nes Ziona, IL
• Shmaryahu Blumberg · Nesher, IL

Key dates

• Filing date: May 10, 1974
• Grant date: Mar 22, 1977
• Expiry date: May 10, 1994

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C08F8/00
• WIPO field: Macromolecular chemistry, polymers
• WIPO sector: Chemistry

Abstract

Enzymes are convalently found to anionic or cationic hydrophilic polymeric carriers formed by essentially complete reaction of pendent anhydride groups of ethylene-maleic anhydride copolymer (EMA) with a diamine selected from the group consisting of hydrazine, P, P'-diaminodiphenylmethane and 1,6-diaminohexane to produce resins having pendent amine groups. The EMA-hydrazide and EMA- P,P'-diaminodiphenylmethane resins can be rendered cationic by reaction with N,N-dimethyl-1,3-propanediamine.