Polyoxetanes which can be used in peptide synthesis
US4013565A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 31, 1974 |
| Grant date | Mar 22, 1977 |
| Priority date | — |
| Expiry date | Jul 31, 1994 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC08G65/329
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Polyoxetanes are provided which consist essentially of a plurality of units of the formula: ##EQU1## AND OPTIONALLY, OF UNITS OF AT LEAST ONE OF THE FORMULAE: ##EQU2## in which: EACH OF X.sub.1 and X.sub.2, which may be identical or different, represents a chlorine or bromine atom, PA1 Y is as defined under X.sub.1 or represents a radical of formula --O--Ar--CH.sub.2 X.sub.2 or --O--Ar', PA1 Each of the Y.sub.1 radicals, which may be identical or different, represents a --O--Ar' or --O--Ar--CH.sub.2 X.sub.2 radical, Ar represents a divalent aromatic radical, the two free valencies of which are carried by carbon atoms of one or two aromatic benzene rings and PA1 Ar' represents the radical --ArH, the units (I) to (V) being connected to one another via the oxygen atom with a free valency of one of the units and a methylene group with a free valency of the adjacent unit. These polyoxetanes, by reason of the fact that they swell very well in, for example, methylene chloride, are particularly suitable for use as the support in the preparation of peptides using solid phase synthesis.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.