Preparation of asymmetric iminodibenzyl compounds
US4013639A · kind A · utility
Assignees
Inventors
Key dates
| Filing date | Jul 24, 1973 |
| Grant date | Mar 22, 1977 |
| Priority date | — |
| Expiry date | Jul 24, 1993 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D223/22
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Iminodibenzyl derivatives of the formula: ##SPC1## Wherein R and R.sup.1 each represent hydrogen, halogen, amino, sulfamoyl, lower alkyl, lower alkoxy or lower alkanoyl, provided that R and R.sup.1 can not both be hydrogen and when R and R.sup.1 are the same, they are located at positions asymmetric to each other, are produced in high purity and yield by a series of reactions which proceed through novel 2,2'-dinitrostilbene or 2,2'-diaminostilbene and 2,2'-diaminodibenzyl derivatives. The reaction sequence involves condensation, reduction and ring-closure reactions to give asymmetric as well as symmetric iminodibenzyl derivatives. The resulting iminodibenzyl derivatives may be converted to useful pharmaceutical compounds having anti-depressant, analgesic or anti-allergic properties.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.