Patent · US Expired

Cephalosporin derivatives

US4014869A · kind A · utility

5Cited by
1References
7Claims
0Family size

Assignee

Inventors

Key dates

Filing dateDec 2, 1974
Grant dateMar 29, 1977
Priority date
Expiry dateDec 2, 1994

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D499/00
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Novel antibiotic compounds which are 7.beta.-acrylamidoceph-3-em-4-carboxylic acids, and 6.beta.-acrylamidopenam-3-carboxylic acids and non-toxic derivatives thereof wherein the acrylamido group has the structure ##STR1## wherein A is aryl group and B is a substituted or unsubstituted lower alkyl, lower alkenyl or lower alkynyl group; or an aryl, cycloalkyl or cycloalkenyl group. These compounds possess antibacterial activity against gram-positive and gram-negative organisms coupled with stability to .beta.-lactamases. The invention further relates to the administration of the compounds.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.