Substituted 4'-hydroxyphenyl guanidines and methods of using the same
US4014934A · kind A · utility
46Cited by
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Key dates
| Filing date | Oct 29, 1974 |
| Grant date | Mar 29, 1977 |
| Priority date | — |
| Expiry date | Oct 29, 1994 |
Classification
- Technology area (CPC A)Human Necessities
- CPC primaryA61K31/47
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Novel aromatic guanidine compounds having the formula: ##STR1## wherein: R.sub.1 is hydroxyl, methyl or hydroxymethyl and R.sub.2 is hydrogen or methyl, are found to have biological activity. The guanidine compounds and their salts are shown to be active as vasoconstrictor agents and create useful pharmaceutical preparations when deployed with a pharmaceutically acceptable carrier for administration to a host, e.g., man, requiring vasoconstrictive therapy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.