Patent · US Expired

1-Aryl-2-oxo-2,4,5,6,7,7a-hexahydro-indoles, salts, pharmaceutical compositions and methods of use

US4015002A · kind A · utility

2Cited by
3References
8Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 1, 1975
Grant dateMar 29, 1977
Priority date
Expiry dateAug 1, 1995

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D209/34
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

This invention relates to 1-aryl-2-oxo-2,4,5,6,7,7a-hexahydro-indoles, and acid addition salts thereof. In particular, the compounds have (.beta.-aminoethoxy- or .gamma.-amino-propoxy)-phenyl substituents, the amino groups in each case either being joined to two C.sub.1.sub.-5 alkyl groups or forming part of a heterocyclic group such as a pyrolidino, piperidino or morpholino group. Compounds in accordance with the invention have been found to exhibit interesting actions on the cardiovascular system in particular as vasodilators.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.