1-Aryl-2-oxo-2,4,5,6,7,7a-hexahydro-indoles, salts, pharmaceutical compositions and methods of use
US4015002A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 1, 1975 |
| Grant date | Mar 29, 1977 |
| Priority date | — |
| Expiry date | Aug 1, 1995 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D209/34
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
This invention relates to 1-aryl-2-oxo-2,4,5,6,7,7a-hexahydro-indoles, and acid addition salts thereof. In particular, the compounds have (.beta.-aminoethoxy- or .gamma.-amino-propoxy)-phenyl substituents, the amino groups in each case either being joined to two C.sub.1.sub.-5 alkyl groups or forming part of a heterocyclic group such as a pyrolidino, piperidino or morpholino group. Compounds in accordance with the invention have been found to exhibit interesting actions on the cardiovascular system in particular as vasodilators.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.