1,2,5,6-Tetrahydro-4H-pyrrolo(3,2,1-j)quinolin-2-ones
US4015005A · kind A · utility
3Cited by
1References
16Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jun 23, 1975 |
| Grant date | Mar 29, 1977 |
| Priority date | — |
| Expiry date | Jun 23, 1995 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D471/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention discloses 1,2,5,6-tetrahydro-4H-pyrrolo-(3,2,1-ij)quinolin-2-ones having pharmacological activity in animals and useful as CNS depressant agents. The compounds may be prepared by treating a haloacetyl derivative of 1,2,3,4-tetrahydroquinoline with a Friedel-Crafts catalyst. The haloacetyl derivative of 1,2,3,4-tetrahydroquinoline may be prepared by reacting 1,2,3,4-tetrahydroquinoline with a haloacetyl halide at a mole ratio of 2:1 in the presence of an inert, organic solvent.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.