Substrate for the quantitative determination of enzymes
US4016042A · kind A · utility
29Cited by
2References
12Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jun 30, 1975 |
| Grant date | Apr 5, 1977 |
| Priority date | — |
| Expiry date | Jun 30, 1995 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/802
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
A synthetic substrate having the structure EQU R.sup.1 -- Pro -- X -- Y -- NH -- R.sup.2, wherein R.sup.1 is a blocking group, --NH--R.sup.2 is a chromogenic or fluorescent group, X represents a phenylalanyl, .beta.-cyclohexylanyl, phenylglycyl or tyrosyl group, and Y represents a protonized arginyl or lysyl group, is disclosed. This substrate is useful for the quantitative determination of proteolytic enzymes of class E.C. 3.4.4., except thrombin and thrombin-like enzymes.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.