N-Substituted erythromcylamines and salts thereof

US4016263A · kind A · utility

Assignee

• Boehringer Ingelheim GmbH · DE

Inventors

• Bernd Wetzel · Biberach an der Riß, DE
• Eberhard Woitun · Biberach an der Riß, DE
• Roland Maier · Biberach an der Riß, DE
• Wolfgang Reuter
• Hanns Goeth · Biberach an der Riß, DE
• Uwe Lechner · Biberach an der Riß, DE

Key dates

• Filing date: Mar 29, 1976
• Grant date: Apr 5, 1977
• Expiry date: Mar 29, 1996

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07H17/08
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Compounds of the formula ##STR1## wherein E is ##STR2## R.sub.1 is hydrogen; straight or branched alkyl of 1 to 3 carbon atoms; (alkoxy of 1 to 5 carbon atoms)-(alkyl of 1 to 3 carbon atoms); phenyl; or benzyl; PA1 R.sub.2 is hydrogen; hydroxyl; straight or branched alkyl of 1 to 3 carbon atoms; or phenyl; PA1 R.sub.3 is hydroxyl; alkanoyloxy of 1 to 5 carbon atoms; benzoyloxy; straight or branched alkoxy of 1 to 5 carbon atoms; amino; mono(alkyl of 1 to 5 carbon atoms)-amino; dialkyl-amino, where the sum of carbon atoms in the alkyls is from 2 to 8, inclusive; mono(hydroxy-alkyl of 1 to 4 carbon atoms) -amino; di(hydroxy-alkyl)-amino, where the sum of carbon atoms in the alkyls is from 2 to 8, inclusive; phenyl(alkyl of 1 to 2 carbon atoms)-amino; phenyl-amino, where the phenyl moiety may optionally have one or more halogen, alkyl of 1 to 3 carbon atoms, alkoxy of 1 to 3 carbon atoms or hydroxyl substituents attached thereto; (alkanoyl of 1 to 5 carbon atoms)-amino; phenyl(alkanoyl of 1 to 5 carbon atoms)-amino; benzoyl-amino; methoxybenzoyl-amino; halobenzoyl-amino; carboxybenzoyl-amino; p-tolylsulfonamino; -HN-NR.sub.4 R.sub.5, where R.sub.4 and R.sub.5 are alkyl of 1 to 3 carbo…