Patent · US Expired

Tetralone and indanone compounds

US4016281A · kind A · utility

11Cited by

6References

29Claims

0Family size

Assignee

Merck Patent GmbH · DE

Inventors

Rochus Jonas · Darmstadt, DE
Jurgen Uhl · Seeheim-Jugenheim, DE
Helmut Muller-Calgan · Darmstadt, DE
Klaus Irmscher

Key dates

Filing date	Feb 18, 1976
Grant date	Apr 5, 1977
Priority date	—
Expiry date	Feb 18, 1996

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07D211/52
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

Tetralone and indanone compounds of the formula ##STR1## wherein R.sup.1 is H, OH, alkoxy of 1-4 carbon atoms, cycloalkoxy of 3-6 carbon atoms, F, Cl, Br, NO.sub.2, monoalkylamino or dialkylamino, wherein each alkyl is of 1-4 carbon atoms, alkanoyloxy of 1-6 carbon atoms or alkanoylamino of 1-4 carbon atoms; R.sup.2 is OH or alkoxy of 1-4 carbon atoms or R.sup.1 and R.sup.2 collectively are methylenedioxy; R.sup.3 is H or CH.sub.3 ; Ar is phenyl or phenyl substituted by up to 5 of alkyl of 1-4 carbon atoms, alkoxy of 1-4 carbon atoms, F, Cl, Br or CF.sub.3 ; n is 1 or 2, and physiologically acceptable acid addition salts thereof, are central nervous system depressants.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.