Biguanide compounds and anti-diabetic compositions

US4017539A · kind A · utility

Assignee

• Boehringer Mannheim GmbH · DE

Inventors

• Elmar Bosies · Weinheim, DE
• Kurt Stach
• Felix Helmut Schmidt
• Ruth Heerdt · Mannheim, DE
• Helmut Weber · Webster, US

Key dates

• Filing date: May 7, 1975
• Grant date: Apr 12, 1977
• Expiry date: May 7, 1995

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07C279/26
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

New biguanide compounds of the formula: ##STR1## wherein A is saturated or unsaturated cycloaliphatic hydrocarbyl, and the physiologically compatible salts thereof; display outstanding anti-diabetic effectiveness in the treatment of diabetes mellitus, without showing the typical side effects of biguanide treatment, viz., lactacidosis.