Patent · US Expired

Instrument for the detection of Neisseria gonorrhoeae without culture

US4018653A · kind A · utility

74Cited by
3References
4Claims
0Family size

Assignee

Inventor

Key dates

Filing dateDec 30, 1974
Grant dateApr 19, 1977
Priority date
Expiry dateDec 30, 1994

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S435/947
  • WIPO fieldMedical technology
  • WIPO sectorInstruments

Abstract

A non-culture method and instrument for a rapid presumptive test for gonorrhea in which a specimen of exudate from a suspected case is placed in direct contact with a pledget containing a compound which reacts with Neisseria gonorrhoeae to produce a color change. The pledget, before the test, is in a dry condition and is activated by a wetting agent such as saline, when placed in contact with the pledget. The chemical compound used and incorporated into the pledget is selected from a group consisting of phenylenediamines. The instrument used consists of a flexible tube containing a fluid-filled frangible ampul at one end and the chemically impregnated pledget disposed immediately above same. A separate sterile swab is supplied for taking the specimen. The swab containing the specimen is inserted into the flexible tube. The flexible tube is then squeezed at the ampul portion, releasing the wetting agent by breaking the frangible ampul. The wetting agent when thus released activates the reagents in the pledget. A downward pressure of the swab containing the specimen places it in direct contact with the activated pledget. If gonorrhea is present in the specimen on the swab, a distinct…

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.