Derivatives of 1-phenoxy-3-amino-propane-2-ol and process for their production
US4018778A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jul 12, 1974 |
| Grant date | Apr 19, 1977 |
| Priority date | — |
| Expiry date | Jul 12, 1994 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D213/50
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The present invention relates to pharmacologically valuable new derivatives of 1-phenoxy-3-amino-propane-2-ol and process for their production. The new derivatives of 1-phenoxy-3-amino-propane-2-ol are suitable for the treatment and prophylaxis of diseases of the heart. Some possess pronounced .beta.-adrenalytic or anti-arythmic properties. These new derivatives have the structural formula ##STR1## wherein X signifies ##STR2## and the phenyl nucleus I may be mono-, di- or trisubstituted by alkyl, alkenyl, alkinyl, cycloalkyl, cycloalkenyl, alkoxy, alkenyloxy, phenyl, halogen or the radical --NR.sub.1 R.sub.2, in which R.sub.1 stands for alkyl or acyl and R.sub.2 for hydrogen or alkyl, together with their aldehyde condensation products and their acid addition salts.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.