Continuous process of producing pancreatin and product thereof

US4019958A · kind A · utility

Assignee

• Kali-Chemie Pharma GmbH · DE

Inventors

• Hans Hell · Wiesbaden, DE
• Gunter Peschke
• Horst Oppermann · Fürstenberg/Havel, DE
• Rudolf Kaufung
• Siegfried Funke
• Werner Stuhmer

Key dates

• Filing date: Mar 19, 1976
• Grant date: Apr 26, 1977
• Expiry date: Mar 19, 1996

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S435/814
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

A freely flowable pancreatin of high amylolytic, lipolytic, and proteolytic activity, of a low germ content and substantially free of pathogenic germs and fibrous tissue material, of a high bulk weight between about 500 g./liter and about 700 g./liter and a very fine particulate size is produced according to the continuous process of extracting finely comminuted pancreas glands with a mixture of chlorinated hydrocarbons and fluoro-chloro-carbons and, if required, water, separating the fat-containing solvent phase, and recovering pancreatin from the enzyme phase.