Process for the preparation of 5-substituted resorcinols and related intermediates
US4020098A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Jul 9, 1975 |
| Grant date | Apr 26, 1977 |
| Priority date | — |
| Expiry date | Jul 9, 1995 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C69/94
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
According to the present invention, 5-substituted resorcinols of the formula I ##STR1## wherein R.sub.1 represents a hydrocarbon radical, optionally unsubstituted or substituted by inert substituents, are prepared by reacting a carboxylic acid ester of the formula II EQU r.sub.1 -- c .tbd. c -- co -- o -- r.sub.2 (ii) wherein R.sub.2 represents a non-aromatically bound lower hydrocarbon radical, in the presence of an alkaline condensation agent, with a diester of 3-oxoglutaric acid of the formula III EQU r.sub.3 --o--co--ch.sub.2 --co--ch.sub.2 --co--o--r.sub.4 (iii) wherein R.sub.3 and R.sub.4 represent non-aromatically bound lower hydrocarbon radicals; hydrolyzing the resulting dihydroxyisophthalic acid acid ester of the formula IV ##STR2## and decarboxylating the hydrolyzed product, a specific embodiment is the preparation of 5-pentylresorcinol.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.