Shortened analogs of somatostatin
US4020157A · kind A · utility
4Cited by
3References
36Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jul 8, 1975 |
| Grant date | Apr 26, 1977 |
| Priority date | — |
| Expiry date | Jul 8, 1995 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/16
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Compounds of the formula 1 or 1a ##STR1## EQU HSCH.sub.2 CH(R)CO--Lys--Asn--Phe--Phe--Trp--Lys--Thr--Phe--Thr--Ser--NHCH.sub.2 CH.sub.2 SH (1a) In which R is hydrogen or NHR.sup.1 in which R.sup.1 is lower aliphatic acyl containing from 1 - 6 carbon atoms or benzoyl, and pharmaceutically acceptable salts thereof are disclosed. The compounds of formulae 1 and 1a are useful for the management of diabetes and the treatment of acromegaly in mammals. Methods for their use also are disclosed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.