1,3-Dioxo-2-[(methoxyphenethyl-amino)-alkyl]-4,4-dimethyl-isoquinolines and salts thereof useful as hypotensive agents
US4021558A · kind A · utility
6Cited by
4References
4Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Jan 22, 1976 |
| Grant date | May 3, 1977 |
| Priority date | — |
| Expiry date | Jan 22, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D217/24
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Compounds of the formula ##STR1## wherein R.sub.1 is hydrogen, halogen, methoxy or methylthio, R.sub.2 is hydrogen or methoxy, PA1 n is 2 or 3, PA1 R.sub.3 is hydrogen or methyl, and PA1 R.sub.4 and R.sub.5, which may be identical to or different from each other, are each hydrogen or methoxy, and non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as the salts are useful as hypotensives, sedatives, antiarrhythmics and bradycardiacs.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.