Neuroleptic piperidine compounds

US4021564A · kind A · utility

Assignee

• AB Ferrosan · SE

Inventors

• Sven E. H. Hernestam · Malmö, SE
• Anders Bjork · Bjärred, SE
• Aina L. Abramo · Bjärred, SE
• Bengt E. S. Kjellberg

Key dates

• Filing date: May 3, 1976
• Grant date: May 3, 1977
• Expiry date: May 3, 1996

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D211/50
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Novel 1-substituted-4-aroyl-4-hydroxy and -4-acyloxypiperidines and acid addition salts thereof, useful as central nervous system depressants and neuroleptics with pronounced antipsychotic effects, are disclosed. Methods of making same, pharmaceutical compositions thereof, a method of treating therewith, and important and novel intermediates for the production thereof, are also disclosed.