Diphenylbutylpiperidines

US4024264A · kind A · utility

Assignee

• AB Ferrosan · SE

Inventors

• Anders Bjork · Bjärred, SE
• Sven E. H. Hernestam · Malmö, SE
• Bengt E. S. Kjellberg

Key dates

• Filing date: Aug 4, 1975
• Grant date: May 17, 1977
• Expiry date: Aug 4, 1995

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D211/50
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Novel 4,4-diphenylbutyl-1-(4-benzoyl-4-hydroxy or acyloxy)-piperidines and acid addition salts thereof, useful as central depressants, e.g., neuroleptics (anti-psychotics), are disclosed. Methods of making same, pharmaceutical compositions thereof, a method of treating therewith, and important and novel intermediates for the production thereof, namely, 4-benzoyl-4-hydroxypiperidines, are also disclosed, as well as 4-benzoyl-1-(4,4-diphenylbutyl)-piperidines, which are also useful intermediates.