Benzylamine derivatives and process for preparing them

US4024274A · kind A · utility

Assignee

• Hoechst GmbH · DE

Inventors

• Eike Druckrey
• Bernd Knabe
• Hans-Jochen Lang · Hofheim, DE
• Milos Babej
• Roman Muschaweck

Key dates

• Filing date: Jan 21, 1975
• Grant date: May 17, 1977
• Expiry date: Jan 21, 1995

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D319/18
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

N-Cycloalkyl-benzylamine derivatives of the formula ##STR1## in which R.sup.1 represents hydrogen or lower alkyl of 1 to 4 carbon atoms, R.sup.2 represents a cycloalkyl radical of a total of 7 to 12 carbon atoms which may be alkyl-substituted and may contain hydrocarbon bridges of 1 to 3 carbon atoms, R.sup.3 represents hydrogen, alkoxy of 1 to 4 carbon atoms, R.sup.4 represents hydrogen or alkoxy of 1 to 4 carbon atoms or halogen, and R.sup.5 represents alkoxy of 1 to 4 carbon atoms, methylene dioxy, ethylene dioxy, benzyloxy or halogen, and the physiologically tolerated salts thereof are disclosed as having diuretic and saluretic activity.