Prostaglandin analogues
US4025546A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 6, 1975 |
| Grant date | May 24, 1977 |
| Priority date | — |
| Expiry date | Nov 6, 1995 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C405/0033
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention relates to novel prostaglandin analogues, characterized by the general formula: ##STR1## or a racemic mixture thereof, as well as esters, amides, salts and acyl derivatives of these compounds, in which C.sub.n H.sub.2n represent an alkylene (2-5 C) group, PA1 R, r.sub.1, r.sub.2, r.sub.3 represent hydrogen or alkyl (1-4 C), PA1 X represents oxygen or sulphur and PA1 Z represents F, Cl, Br or CF.sub.3 and whereby the symbol .about. means the .alpha. or .beta. configuration. The compounds show a pronounced activity on the uterus and the ovary, owing to which they are very suited for initiating the partus or the termination of pregnancy.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.