Novel sugar ureide and thioureide derivatives
US4025622A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Feb 26, 1975 |
| Grant date | May 24, 1977 |
| Priority date | — |
| Expiry date | Feb 26, 1995 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07H15/18
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Novel sugar ureide and thioureide derivatives are provided by this invention, which exhibit certain antibacterial activity against a variety of gram-positive and gram-negative bacteria and useful in therapeutic treatment of bacterial infections. The compounds have the formula ##STR1## wherein R.sub.1 is a monovalent residue of aldose, aldonic acid and their 2-amino derivatives, R.sub.2 is an aralkyl, heterocyclic, sulfamoylaryl, R.sub.3 CONH or R.sub.4 NH-- where R.sub.3 is a heterocyclic and R.sub.4 is an aryl group and Y is oxygen or sulfur atom, which are prepared by reacting an isocyanate or isothiocyanate of the formula R.sub.1 NC=Y with an amino compound of the formula R.sub.2 NH.sub.2.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.