Acetic acid derivatives having pharmacological activity and compositions containing the same
US4025649A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Jun 18, 1975 |
| Grant date | May 24, 1977 |
| Priority date | — |
| Expiry date | Jun 18, 1995 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C57/03
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Acetic acid derivatives of the formula: ##STR1## and pharmaceutically acceptable alkali metal salts thereof, wherein R represents the radical ##STR2## in which R.sub.1 and R.sub.2, which may be the same or different, each represent an alkyl radical having from 1 to 4 carbon atoms, R.sub.3 represents a hydrogen atom or a methyl radical and n is an integer in the range of from 0 to 3 inclusive. They possess a competitive inhibitory activity with respect to .gamma.-aminobutyric .alpha.-ketoglutaric transaminase as well as antianoxic and anticonvulsant properties and they are useful for treating central neurological disorders whether resulting or not from cerebral ischemia.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.