Chromogenic enzyme substrates
US4028318A · kind A · utility
24Cited by
3References
9Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Nov 14, 1975 |
| Grant date | Jun 7, 1977 |
| Priority date | — |
| Expiry date | Nov 14, 1995 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S930/28
- WIPO fieldBiotechnology
- WIPO sectorChemistry
Abstract
Chromogenic substrates for serine proteases, represented by the formula: EQU R.sub.1 -A.sub.1 -A.sub.2 -Gly-Arg-NH-R.sub.2 or its salts, where R.sub.1 is hydrogen or alkanoyl having from 1 to 12 carbon atoms or cyclohexylcarbonyl or benzoyl or benzoyl substituted with one or two halogen atoms, methylamine or phenyl groups or benzene sulphonyl or toluenesulphonyl, R.sub.2 is nitrophenyl or naphthyl or nitronaphthyl or methoxynaphthyl or quinolyl or nitroquinolyl, A.sub.1 is a single bond or one of the amino acids Gly, Ala, Val, Leu, Ileu, Pro, Met, Phe or Tyr, and A.sub.2 is one of the amino acids Glu, Gln, Asp, or Asn.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.