Process of making gona-1,3,5(10),9(11)-tetraenes

US4029648A · kind A · utility

Assignee

• VEB Jenapharm · DE

Inventors

• Kurt Ponsold · Jena, DE
• Helmut Kasch · Jena, DE

Key dates

• Filing date: Jan 15, 1976
• Grant date: Jun 14, 1977
• Expiry date: Jan 15, 1996

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C25B3/23
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Gona-1,3,5(10),9(11)-tetraenes having the formula ##STR1## IN WHICH FORMULA N IS 1 OR 2, PA1 R.sup.1 is a hydrogen, hydroxy, alkoxy, or alkanoyl substituent, PA1 R.sup.2 is a hydrogen, alkoxy, acetoxy, alkyl, akenyl, or alkynyl substituent, or a substituent having the formula --CH.sub.2 X in which X is a halogen, pseudohalogen, or O-alkyl substituent, or PA1 R.sup.1 or R.sup.2 together are oxygen, or a methyleneoxy or ethylenedioxy substituent, PA1 R.sup.3 is a hydroxy, alkoxy, alkanoyl, or alkoxymethyleneoxy substituent, and PA1 R.sup.4 is a methyl or ethyl substituent, PA1 Are made from gona-1,3,5(10)trienes by electrolysis of a solution thereof in water and/or a primary or secondary alcohol in the presence of an electroconductive compound. The gona-1,3,5(10),9(11)-tetraenes are intermediates for the production of steroidal pharmaceuticals for fertility control in human and animal therapeutics.