Patent · US Expired

Cortical steroid nitrogen mustard compositions and treatment therewith

US4029778A · kind A · utility

5Cited by

5References

32Claims

0Family size

Assignee

Leo Corporation

Inventors

Hans Fex · Helsingborg, SE
Knut Bertil Hogberg
Imre Konyves · Helsingborg, SE

Key dates

Filing date	Mar 13, 1973
Grant date	Jun 14, 1977
Priority date	—
Expiry date	Mar 13, 1993

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07J41/005
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

New 21-esters of corticoid steroid hormones, the esters having an antitumor activity, are prepared by reacting a reactive derivative of the general formula ##STR1## wherein R.sup.1 can be hydrogen, lower alkyl, halogen, or lower alkoxy, X can be oxygen, sulphur, or a monovalent carbon-to-carbon bond, A can be alkylene, aminoalkylene, or lower-alkanoyl aminoalkylene, and A together with X also can be a monovalent carbon-to-carbon bond, with a corticoid steroid.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.