Substituted 2-aminomethyl-6-iodophenols
US4029816A · kind A · utility
26Cited by
6References
14Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 20, 1976 |
| Grant date | Jun 14, 1977 |
| Priority date | — |
| Expiry date | Sep 20, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07F3/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Certain substituted 2-aminomethyl-6-iodophenols and their pharmaceutically acceptable acid addition salts wherein the phenyl nucleus may be further substituted with 1 to 3 nuclear substituents are useful as antihypertensive, diuretic and saluretic agents. These products may be prepared by either iodinating a 2-aminomethyl-3,4,5-substituted phenol or hydrolyzing an appropriately substituted N-(2-hydroxy-3-iodo-4,5,6-substituted benzyl)carboxamide under either acidic or basic conditions.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.