Camptothecin analogues
US4031098A · kind A · utility
45Cited by
1References
4Claims
0Family size
Assignee
Inventor
Key dates
| Filing date | Jan 5, 1976 |
| Grant date | Jun 21, 1977 |
| Priority date | — |
| Expiry date | Jan 5, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D491/22
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Camptothecin analogues showing more potent anti-tumor activity than a naturally occurring alkaloid camptothecin, which also exhibit an immunosuppressive activity, in which the 1-ethyl of camptothecin is replaced by various members of substitutents such as alkyls (except ethyl), alkenyls, alkynyls, aralkyls or aryloylalkyls; being produced from readily accessible starting materials on totally synthetic method newly developed by the present inventor.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.