Substituted 2H,3H-2,1-benzisothiazole-S-oxides, method of use and pharmaceutical compositions thereof
US4031227A · kind A · utility
1Cited by
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19Claims
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Assignee
Inventor
Key dates
| Filing date | Sep 18, 1975 |
| Grant date | Jun 21, 1977 |
| Priority date | — |
| Expiry date | Sep 18, 1995 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D275/06
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
The invention discloses substituted 2H,3H-2,1-benzisothiazole-S-oxides having pharmacological activity in animals and useful as CNS depressant agents. The compounds may be prepared by reacting a substituted 2H,3H-2,1-benzisothiazole with an oxidizing agent. The substituted 2H,3H-2,1-benzisothiazole may be prepared by reacting a substituted .alpha.-methylthio-o-toluidine with one equivalent of an oxidizing agent, followed by treatment with base.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.