Novel thiophene derivatives and their preparation

US4031236A · kind A · utility

Assignee

• SCHERING CORPORATION · US

Inventors

• Hanns Ahrens
• Helmut Biere · Berlin, DE
• Clemens Rufer
• Ralph Schmiechen · Berlin, DE
• Eberhard Schroeder
• Olaf Loge
• Wolfgang Losert
• Ekkehard Schillinger · Berlin, DE

Key dates

• Filing date: May 20, 1975
• Grant date: Jun 21, 1977
• Expiry date: May 20, 1995

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D333/34
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Thiophene derivatives of the formula ##STR1## IN WHICH R.sub.x is --S--CHR.sub.5 --CONHOH or --S--CHR.sub.5 -5-tetrazolyl in which R.sub.5 is H or alkyl of 1-6 carbon atoms and R.sub.y is 0-2 of alkyl or alkoxy of 1-6 carbon atoms or halogen, and their pharmacologically acceptable salts with bases, possess antilipolytic activity.