Benzopyran derivatives

US4032540A · kind A · utility

Assignee

• SCHERING CORPORATION · US

Inventors

• Ulrich Eder · Berlin, DE
• Gerhard Sauer · Berlin, DE
• Gregor Haffer · Berlin, DE
• Jurgen Ruppert
• Rudolf Wiechert · Berlin, DE

Key dates

• Filing date: Mar 5, 1976
• Grant date: Jun 28, 1977
• Expiry date: Mar 5, 1996

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D317/44
• WIPO field: Organic fine chemistry
• WIPO sector: Chemistry

Abstract

Benzopyran derivatives of the formula ##STR1## wherein R.sub.1 and R.sub.3 each are lower alkyl; n is the integer 1 or 2; --A--B-- is >CH--CH.sub.2 - or >CH=CH-; X is a free, esterified or etherified hydroxy group; and Y is H or X and Y collectively are =O; and W is --(CH.sub.2).sub.3 --Z--R.sub.4 ##STR2## --(CH.sub.2).sub.3 --COOR.sub.6 or --(CH.sub.2).sub.3 CN, wherein V is halogen, Z is a ketalized carbonyl group or a free, esterified or etherified hydroxymethylene group; R.sub.4 and R.sub.5 each are lower alkyl and R.sub.6 is alkyl, aryl or aralkyl, are valuable intermediates in the synthesis of steroids.