Mixture of antibiotics produced by new species of streptosporangium

US4032632A · kind A · utility

Assignee

• PFIZER INC. · US

Inventors

• Walter D. Celmer · New London, US
• Walter P. Cullen · East Lyme, US
• Charles E. Moppett · Mystic, US
• John B. Routien · East Lyme, US
• Mark T. Jefferson · Waterford, US
• Riichiro Shibakawa · Handa, JP
• Junsuke Tone · Chita, JP

Key dates

• Filing date: Jul 23, 1976
• Grant date: Jun 28, 1977
• Expiry date: Jul 23, 1996

Classification

• Technology area (CPC Y): Emerging Cross-Sectional Technologies
• CPC primary: Y10S435/822
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Two new species of Streptosporangium, designated Streptosporangium koreanum Routien sp. nov. and Streptosporangium cinnabarinum Routien sp. nov., when subjected to submerged aerobic fermentation, produce the same two new antibiotics. Methods for the recovery and purification of these antibiotics, co-produced with minor antibiotics, are described and some of their antimicrobial properties are outlined.