3,3A,6,6A-Tetrahydrofuro[3,4-b]furan derivatives and anti-ulcer composition containing them
US4032651A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Sep 11, 1975 |
| Grant date | Jun 28, 1977 |
| Priority date | — |
| Expiry date | Sep 11, 1995 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C381/12
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Pharmaceutical compositions containing 3,3a,6,6a-tetrahydrofuro[3,4-b]furan derivatives including canadensolide and 3-epi-dihydrocanadensolide. Novel 3,3a,6,6a-tetrahydrofuro[3,4-b]furan derivatives bearing a variety of substituents in the 3- and 6-positions selected from alkyl, phenyl, alkoxycarbonyl, methylene, benzylthiomethyl and optionally substituted phenylthiomethyl. The compositions and novel compounds show anti-ulcer activity and are useful in the treatment of gastric or duodenal ulcers.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.