Patent · US Expired

3,3A,6,6A-Tetrahydrofuro[3,4-b]furan derivatives and anti-ulcer composition containing them

US4032651A · kind A · utility

2Cited by
1References
4Claims
0Family size

Assignee

Inventors

Key dates

Filing dateSep 11, 1975
Grant dateJun 28, 1977
Priority date
Expiry dateSep 11, 1995

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07C381/12
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Pharmaceutical compositions containing 3,3a,6,6a-tetrahydrofuro[3,4-b]furan derivatives including canadensolide and 3-epi-dihydrocanadensolide. Novel 3,3a,6,6a-tetrahydrofuro[3,4-b]furan derivatives bearing a variety of substituents in the 3- and 6-positions selected from alkyl, phenyl, alkoxycarbonyl, methylene, benzylthiomethyl and optionally substituted phenylthiomethyl. The compositions and novel compounds show anti-ulcer activity and are useful in the treatment of gastric or duodenal ulcers.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.