Patent · US Expired

Assay for myasthenia gravis

US4033722A · kind A · utility

4Cited by
0References
8Claims
0Family size

Assignee

Inventor

Key dates

Filing dateAug 8, 1975
Grant dateJul 5, 1977
Priority date
Expiry dateAug 8, 1995

Classification

  • Technology area (CPC Y)Emerging Cross-Sectional Technologies
  • CPC primaryY10S436/811
  • WIPO fieldMeasurement
  • WIPO sectorInstruments

Abstract

A serum assay system for diagnosis of myasthenia gravis. The assay system includes a complex of acetylcholine receptor protein and a toxin labeled with a radioactive isotope. The complex is incubated with a serum sample from a patient. During incubation, antibodies engendered by myasthenia gravis bind to receptor sites in the complex. The resulting complex containing the antibodies is precipitated by addition of anti-immunoglobulin. Radioactivity in the resulting precipitate is measured and compared with a control.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.