Assay for myasthenia gravis
US4033722A · kind A · utility
Assignee
Inventor
Key dates
| Filing date | Aug 8, 1975 |
| Grant date | Jul 5, 1977 |
| Priority date | — |
| Expiry date | Aug 8, 1995 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S436/811
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
A serum assay system for diagnosis of myasthenia gravis. The assay system includes a complex of acetylcholine receptor protein and a toxin labeled with a radioactive isotope. The complex is incubated with a serum sample from a patient. During incubation, antibodies engendered by myasthenia gravis bind to receptor sites in the complex. The resulting complex containing the antibodies is precipitated by addition of anti-immunoglobulin. Radioactivity in the resulting precipitate is measured and compared with a control.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.