Process for the production of 2-amino-benzothiazoles
US4035379A · kind A · utility
8Cited by
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14Claims
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Assignee
Inventor
Key dates
| Filing date | Jan 22, 1976 |
| Grant date | Jul 12, 1977 |
| Priority date | — |
| Expiry date | Jan 22, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D277/82
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A process for the production of a 2-amino-benzothiazole having the formula: ##STR1## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are the same or different and are hydrogen, halogen, alkyl or alkoxy. A phenylthiourea having the formula: ##STR2## wherein R.sub.1, R.sub.2, R.sub.3 and R.sub.4 are defined as above, is added to a cyclization agent in the absence of a solvent and allowing the phenylthiourea to cyclize to form 2-amino-benzothiazole in salt form. Filtering the salt of the 2-amino-benzothiazole out of the reaction mixture.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.