Butanoic and butenoic acid morpholides
US4035497A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Apr 22, 1976 |
| Grant date | Jul 12, 1977 |
| Priority date | — |
| Expiry date | Apr 22, 1996 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D295/145
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
Alkyl esters, dialkylamides and heterocyclic amides of 4-amino-alkyl-4-cyano-4-phenyl-butanoic and but-2-enoic acids substituted in at least one of the 2 and 3 positions by a C.sub.1 -C.sub.4 alkyl group or by a divalent alkylene radical which together with at least one of the carbon atoms at said 2 and 3 positions forms a carbocyclic ring of 3 to 8 carbon atoms are novel intermediates involved in the preparation of pharmacologically active compounds. They also have pharmacological, in particular central nervous system, especially anti-depressant or cardiovascular activity. Several methods are disclosed for preparing the novel compounds.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.