Ethyleneimine inactivated microorganisms
US4036952A · kind A · utility
13Cited by
2References
31Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 26, 1975 |
| Grant date | Jul 19, 1977 |
| Priority date | — |
| Expiry date | Sep 26, 1995 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC12N2770/32163
- WIPO fieldPharmaceuticals
- WIPO sectorChemistry
Abstract
Microorganisms can be rendered inactive without impairing their antigenicity or immunogenicity by treating the microorganisms with ethyleneimine. The microorganism is placed in a suspension containing ethyleneimine up to a final concentration of 0.005% to 2% V/V. The temperature of the ethyleneimine-containing suspension is maintained between 0.degree. C and 45.degree. C for between a few hours and 2 days. The excess ethyleneimine is destroyed.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.