Patent · US Expired

6-Aminocarbonyl purine 3',5'-cyclic nucleotides

US4038480A · kind A · utility

8Cited by

3References

22Claims

0Family size

Assignee

ICN Pharmaceuticals, Inc. · US

Inventors

Roland K. Robins · Irvine, US
Dennis Shuman · Mission Viejo, US
Kay H. Boswell · Mission Viejo, US

Key dates

Filing date	Sep 17, 1973
Grant date	Jul 26, 1977
Priority date	—
Expiry date	Sep 17, 1993

Classification

Technology area (CPC C)Chemistry; Metallurgy
CPC primaryC07H19/20
WIPO fieldOrganic fine chemistry
WIPO sectorChemistry

Abstract

N.sup.6 -Carbamoyl and -carbonyl analogs of adenosine 3',5'-cyclic phosphate (cAMP) are prepared and variously demonstrated to exhibit kinase, adrenal steroidogenisis and lipolysis activation superior to cAMP, inhibit phosphodiesterase, and found to increase cardiac output or, in particular cases, to lower blood pressure.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.