.alpha.-Substituted benzhydrol derivatives and a process for the preparation thereof
US4039589A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Aug 8, 1974 |
| Grant date | Aug 2, 1977 |
| Priority date | — |
| Expiry date | Aug 8, 1994 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07C323/00
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
A compound of the formula: ##STR1## wherein Z is ethyl or vinyl, PA1 R.sub.1 and R.sub.2 are hydrogen, lower alkyl, lower alkenyl or trihalomethyl, PA1 R.sub.3 and R.sub.4 are hydrogen, lower alkyl, lower alkenyl, trihalomethyl, cyclopentyl, benzyl or phenyl, and PA1 R.sub.5 is lower alkyl, lower alkenyl, trihalomethyl, cyclopentyl, benzyl, or phenyl with the proviso that where R.sub.1, R.sub.2, R.sub.3 and R.sub.4 each is hydrogen, R.sub.5 is not methyl attached to the 4-position of the benzene ring, or a pharmaceutically acceptable acid addition or quaternary ammonium salt thereof is disclosed as effective in the regulation of the liver microsomal enzyme system.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.