Patent · US Expired

Arylamino pyrimidinic derivatives

US4041030A · kind A · utility

5Cited by
0References
13Claims
0Family size

Assignee

Inventors

Key dates

Filing dateAug 16, 1976
Grant dateAug 9, 1977
Priority date
Expiry dateAug 16, 1996

Classification

  • Technology area (CPC C)Chemistry; Metallurgy
  • CPC primaryC07D239/42
  • WIPO fieldOrganic fine chemistry
  • WIPO sectorChemistry

Abstract

Compounds of the formula ##STR1## WHEREIN Ar is phenyl or phenyl substituted by one or more halogens, a trifluoromethyl, a methylenedioxy, one or more methoxy, an alkyl having one to 4 carbon atoms or a dimethylamino, And R is ##STR2## wherein R.sub.1 and R.sub.2 each are hydrogen or alkyl of 1 to 4 carbon atoms, or ##STR3## PYRROLIDINO, MORPHOLINO, PIPERIDINO OR PIPERAZINO N'-substituted by alkyl of 1 to 4 carbon atoms, or phenyl, or R is para-2-morpholino ethylamino carbonyl, and R.sub.3 is hydrogen or methyl. The compounds are obtained by reacting 2-Ar-2-chloro-6-methyl pyrimidine, with ##STR4## The compounds possess sedative, antiulcerous, antibronchoconstrictive, anticholinergic, diuretic, analgesic myorelaxant and antianoximia properties.

Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.