3,2-Benzoxazepine derivatives
US4041048A · kind A · utility
Assignee
Inventors
Key dates
| Filing date | Nov 14, 1974 |
| Grant date | Aug 9, 1977 |
| Priority date | — |
| Expiry date | Nov 14, 1994 |
Classification
- Technology area (CPC C)Chemistry; Metallurgy
- CPC primaryC07D267/04
- WIPO fieldOrganic fine chemistry
- WIPO sectorChemistry
Abstract
3,2-Benzoxazepines of the formula ##STR1## and their preparation. In formula (I), R respesents hydrogen or lower alkyl; R.sup.1 represents hydrogen, lower alkyl, lower alkenyl, hydroxy-lower alkyl, carbamyloxy-lower alkyl, acyl, amidino, carbamyl, mono- or di-substituted carbamyl; R.sup.2 may be in position 7 or 8 of the benzoxazepine ring and represents hydrogen, nitro, amino, acetamino or halo. The compounds are prepared by reacting 1,2,4,5-tetrahydro-3,2-benzoxazepine with a reactant which reacts with a secondary amino group to give substitution in the 2-position. The compounds have anti-inflammatory and central nervous system activity.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.