Quaternary N-.beta.-substituted N-alkyl-nortropine benzilates

US4042700A · kind A · utility

Assignee

• Boehringer Ingelheim GmbH · DE

Inventors

• Rolf Banholzer · Stuttgart, DE
• Rudolf Bauer · Hallerndorf, DE
• Alex Heusner
• Werner Schulz

Key dates

• Filing date: Sep 3, 1976
• Grant date: Aug 16, 1977
• Expiry date: Sep 3, 1996

Classification

• Technology area (CPC C): Chemistry; Metallurgy
• CPC primary: C07D451/02
• WIPO field: Pharmaceuticals
• WIPO sector: Chemistry

Abstract

Compounds of the formula ##STR1## wherein ONE OF R and R' is alkyl of 1 to 4 carbon atoms, PA1 The other of R and R' is .beta.-haloethyl or .beta.-hydroxyethyl, and PA1 X is a pharmacologically acceptable anion, preferably halogen; The compounds as well as the salts are useful as spasmolytics, bronchospasmolytics and inhibitors of excessive stomach juice secretion.