Oxazepam derivatives for immunoassay reagents
US4043989A · kind A · utility
35Cited by
5References
6Claims
0Family size
Assignee
Inventors
Key dates
| Filing date | Sep 11, 1975 |
| Grant date | Aug 23, 1977 |
| Priority date | — |
| Expiry date | Sep 11, 1995 |
Classification
- Technology area (CPC Y)Emerging Cross-Sectional Technologies
- CPC primaryY10S530/807
- WIPO fieldMeasurement
- WIPO sectorInstruments
Abstract
Compounds are provided for use in the preparation of reagents which can be used in immunoassays for benzdiazepines, particularly as their urinary metabolites. The compounds are non-oxo-carbonyl derivatives conjugated to the 3-position of the benzdiazepine, which in turn are conjugated to antigenic polypeptides for formation of antibodies for use in immunoassays. The antibodies produced, when employed in immunoassays, are found to be able to detect the ingestion of a wide variety of benzdiazepine drugs as determined by positive results with the urine of the patient.
Source: USPTO / EPO open patent data. Objective bibliographic and citation counts.